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KMID : 0358420070500101299
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Korean Journal of Obstetrics and Gynecology
2007 Volume.50 No. 10 p.1299 ~ p.1307
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Contemporary clinical trials in uterine corpus malignancies
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Ryu Hee-Sug
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Abstract
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Uterine cancer is the most common gynecologic malignancy in Western countries. In Korea, its incidence has been rising, and the increased incidence is associated with a rising death rate. The first two decades of endometrial cancer study by the GOG began with a prospective, surgicopathologic staging trial that was the cornerstone for development of all subsequent trials. The therapeutic strategies were tailored to disease extent - low risk, intermediate risk, and high risk groups of patients. There were great advances in the area of chemotherapeutic agents through a number of extensive phase II trials. New trials of these agents have been opened for the patients with advanced or recurrent uterine cancers.
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KEYWORD
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Endometrial cancer, Uterine sarcoma, Clinical trials
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